Abstract:Objective To investigate the research hotspots and development trends of dandelion in the field of cancer prevention and treatment.Methods The relevant literature on the prevention and treatment of tumors with dandelion was retrieved from China National Knowledge Infrastructure, Wanfang Data, VIP website, and Web of Science core databases from January 1, 2000 to November 24, 2023. The CiteSpace software was used to visualize the authors, publishing institutions, and keywords.Results Totally, 663 Chinese papers and 120 English papers were included, and the annual number of publications showed an overall upward trend. There were 698 authors and 336 institutions extracted from Chinese papers, and 317 authors and 189 institutions from English papers. A total of 593 Chinese keywords were extracted, and the top five were dandelion, chemical composition, breast cancer, pharmacological effects, and drug rules. A total of 337 English keywords were extracted, and the top five were apoptosis, dandelion, taraxacum officinale, activation, and expression.Conclusion The research on the prevention and treatment of tumors with dandelion has received continuous attention at home and abroad. The research hotspots of Chinese literature were network pharmacology, drug use rules, data mining, etc. The research hotspots in English literature were antioxidant, selective induction, hepatocellular carcinoma, etc. In general, there were relatively less clinical studies, so it is recommended to strengthen the connection between basic research and clinical practice, focus on translational research, and explore fully the therapeutic value of traditional Chinese medicine.