Abstract:Ovarian cancer is one of the female gynecological malignancies, with the highest mortality rate among the female reproductive system malignancies. The metastasis of ovarian cancer is mainly based on extensive pelvic and abdominal implantation, and pericardial metastasis is extremely rare. In this paper, a 54-year-old woman with recurrent pericardial metastasis of ovarian cancer was reported. By timely detection of pericardial metastasis, timely pericardial puncture treatment and chemotherapy intervention, the symptoms were relieved, thereby prolonging the survival of the patient and improving survival benefits. Based on this case, relevant literature was reviewed and discussed to provide clinical data and treatment experience for rare pericardial metastasis of ovarian cancer.