肿瘤患者化疗后骨髓抑制发生风险预测模型的研究进展★

Risk prediction models for chemotherapy-induced myelosuppression in cancer patients

摘要:

骨髓抑制是肿瘤患者化疗后出现的最常见、最严重的不良反应之一。作为一种预测、筛查、评估工具，骨髓抑制发生风险预测模型可帮助医护人员早期识别骨髓抑制高风险人群。本文整合肿瘤患者化疗后骨髓抑制危险因素，总结骨髓抑制发生风险预测模型，并对预测模型的构建方法、验证方法、预测性能进行比较，分析存在的不足，为临床早期识别高危人群、及时采取有效预防措施提供依据。

Abstract:

Myelosuppression is one of the most common and serious adverse reactions after chemotherapy in cancer patients. As a tool of assessment, screening and prediction, the risk prediction models of myelosuppression can help medical staff identify high-risk groups of myelosuppression at early stage. This study integrated the risk factors of myelosuppression of cancer patients after chemotherapy, and summed up the risk prediction models for myelosuppression. The construction methods, verification techniques, and predictive performance of various models were compared here, and their shortcomings were also analyzed. It provided reference for early identification of high-risk groups of myelosuppression and timely effective preventive measures.