巴氯芬过量致晚期直肠癌患者昏迷1例并文献复习

doi:10.3969/j.issn.2095-1264.2024.04.21

首页 > 过刊浏览>2024年第4期 >516-520. DOI:10.3969/j.issn.2095-1264.2024.04.21

巴氯芬过量致晚期直肠癌患者昏迷1例并文献复习
DOI:
                        10.3969/j.issn.2095-1264.2024.04.21
                    
作者:
                        
                        
                    
作者单位:1.荆州市中心医院 药学部，湖北 荆州，434020;2.华中科技大学同济医学院附属同济医院，湖北 武汉，430000
作者简介:张标，男，硕士，主管药师，研究方向：临床药学。
通讯作者:杨远荣，男，硕士生导师，主任药师，研究方向：医院药事管理。
中图分类号:R730.6;R735.3+7
基金项目:

Coma caused by baclofen overdose in a patient with advanced rectal cancer: a case report and literature review

Author:

Affiliation:

1.Department of Pharmacy, Jingzhou Central Hospital, Jingzhou, 434020, Hubei, China;2.Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430000, Hubei, China

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摘要:

呃逆是临床常见病症，在肿瘤患者中发生率可能更高，一般可通过去除诱因、药物治疗及物理疗法缓解。巴氯芬是治疗顽固性呃逆的有效药物，但不良反应较多。本文介绍了1例不合理应用巴氯芬致严重不良反应的病例，以期为临床工作提供一定参考。

Abstract:

Hiccup is a common clinical disease, and its incidence may be higher in tumor patients. It can usually be alleviated by removing the trigger, taking drug therapy, and getting physical therapy. Baclofen is an effective drug for the treatment of intractable hiccup, but it has many adverse effects. This paper presents a case of severe adverse drug reaction caused by unreasonable use of baclofen, in order to provide some reference for clinical work.